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Addiction is the compulsive physiological need for and use of a habit-forming substance, whether it is drugs, alcohol, nicotine or even food. Addicts continue to seek out their drugs of choice despite physical, psychological and social harm.

Researchers at the Emory National Primate Research Center (EPC) are working to decipher the biological and psychological backgrounds of addiction and are paving the way for a new class of drugs to target addiction and obesity.

EPC researchers developed and tested one such medication, RTI-336, aimed at treating cocaine addiction. Evaluation in human clinical trials showed the medication could be a useful adjunct in the treatment of cocaine dependence. The progress with this compound is one example of collaborative research programs at the EPC.

EPC Investigators Studying Addiction